Top 10 leading causes of infant death in the U.S. (2021)

The United States of America has an infant mortality rate of 558.3 infant deaths per 100,000 live births. From the last available data, the top 10 leading causes were responsible for over 67% of infant death.

Infant death U.S.

Here are the top 10 leading causes of infant death in the United States ranked by the number of deaths.

RankNameDeath
1Congenital malformations4,301
2Low birth weight3,445
3Unintentional injuries1,266
4Sudden infant death syndrome1,248
5Maternal complications1,245
6Cord and placental complications742
7Bacterial sepsis of newborn603
8Respiratory distress of newborn424
9Diseases of the circulatory system406
10Necrotizing enterocolitis354

All other causes are responsible for 6,887 deaths. Taking it to a total of 20,921. The data for this ranking is from the CDC.

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